HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 977206Generated: October 25, 2026
Piperidine → 5-[(3,4-Dihydroxy-5-cyanophenyl)methylidene]-2-thioxothiazolidin-4-one
https://huagongshe.com/reaction/977206
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Rhodanine | HCID 1201546 | — |
| Reactant | 5-Formyl-2,3-dihydroxybenzonitrile | HCID 15292583 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5-[(3,4-Dihydroxy-5-cyanophenyl)methylidene]-2-thioxothiazolidin-4-one | HCID 53780783 | — |
Reaction Steps
A solution containing 0.61 g of rhodanine, 0.72 g of 3,4-dihydroxy-5-cyanobenzaldehyde and 0.1 ml of piperidine in 10 ml of acetic acid was heated for 4 h at 100° C. The product was filtered and washed with 2-propanol. Yield 0.35 g, mp >350° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05614541 |
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| Source dataset | uspto-grants-1997_03 |
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| ORD ID | ord-3cc49db8fd1e455285acc574fa55ec6c |
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| Source note | uspto-grants-1997_03 |
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