HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl (2S)-2-amino-3-phenylpropanoate → tert-butyl (2R)-2-[3-(4-cyanophenyl)-2-oxo-5-oxazolidinylcarbonylamino]-3-phenylpropionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl (2S)-2-amino-3-phenylpropanoate | HCID 6931633 | — |
| Reactant | 3-(4-Cyanophenyl)-2-oxo-5-oxazolidinecarboxylic acid | HCID 15340939 | — |
| Product | tert-butyl (2R)-2-[3-(4-cyanophenyl)-2-oxo-5-oxazolidinylcarbonylamino]-3-phenylpropionate | HCID 70116075 | — |
Reaction Steps
In analogy to Example 4, reaction of phenylalanine tert-butyl ester and 3-(4-cyanophenyl)-2-oxo-5-oxazolidinecarboxylic acid [obtainable according to Example 1] gives tert-butyl (2R)-2-[3-(4-cyanophenyl)-2-oxo-5-oxazolidinylcarbonylamino]-3-phenylpropionate, m.p. 72°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05614535 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-8418d26b770a4197a6b5305827ac126b |
| Source note | uspto-grants-1997_03 |