Trifluoroacetic acid → Trifluoroacetate

Participants

Reaction Steps

0.53 g of tert-butyl 2-{1-[3-(4-tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperidyloxy}acetate is stirred in 10 ml of trifluoroacetic acid at room temperature. After customary workup, the crude product is triturated with ether and dried. 2-{1-[3-(4-aminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperidyloxy}acetic acid, trifluoroacetate, is obtained, FAB (M+1): 378.

Provenance & Evidence