HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-(4-Aminomethylphenyl)-2-oxo-5-oxazolidinecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-(4-Tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinecarboxylic acid | HCID 19965556 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 3-(4-Aminomethylphenyl)-2-oxo-5-oxazolidinecarboxylic acid | HCID 19965536 | — |
Reaction Steps
3.36 g of 3-(4-tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinecarboxylic acid [obtainable according to Example 14; m.p. 166°] are stirred at room temperature for 1 h in a mixture of 30 ml of ether and 30 ml of dioxane, which has been saturated beforehand with HCl gas. The precipitate is then filtered off with suction and washed with ether. 3-(4-Aminomethylphenyl)-2-oxo-5-oxazolidinecarboxylic acid is obtained, m.p. 211°-212°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05614535 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-82300ad76a614e8c8509a7f0a1ad9b68 |
| Source note | uspto-grants-1997_03 |