HCID 70108314, compound → HCID 19965672, compound

Participants

Reaction Steps

A mixture of (E)-4-[2-[5-methyl-2-(2-naphthyl)-4-oxazolyl]vinyl]benzyl alcohol (7.80 g), activated manganese dioxide (15.6 g) and chloroform (300 ml) was stirred at room temperature for 1 day. After the manganese dioxide was filtered off, the filtrate was concentrated under reduced pressure; the resulting crystal was recrystallized from dichloromethane-methanol to yield (E)-4-[2-[5-methyl-2-(2-naphthyl)-4-oxazolyl]vinyl]benzaldehyde (6.56 g, 85%) as light yellow needles having a melting point of 162°-163° C.

Provenance & Evidence