HCID 53802020, compound → HCID 19965634, compound

HRID 977254Notes

Reaction equation

HRID 977254 reaction equation
[CH3:1][C:2]1[S:6][C:5]([CH2:7][CH2:8][C:9]2[CH:16]=[CH:15][C:12]([CH2:13][OH:14])=[CH:11][CH:10]=2)=[N:4][C:3]=1[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>[O-2].[O-2].[Mn+4]>[CH3:1][C:2]1[S:6][C:5]([CH2:7][CH2:8][C:9]2[CH:16]=[CH:15][C:12]([CH:13]=[O:14])=[CH:11][CH:10]=2)=[N:4][C:3]=1[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 1

HCID 53802020HCID 53802020, compound

Product 1

HCID 19965634HCID 19965634, compound

Reagents, catalysts & solvents 1

HCID 178418406HCID 178418406, compoundCatalyst

Procedure

4-[2-(5-Methyl-4-phenyl-2-thiazolyl)ethyl]benzyl alcohol was oxidized with manganese dioxide in the same manner as in Reference Example 15 to yield 4-[2-(5-methyl-4-phenyl-2-thiazolyl)ethyl]benzaldehyde, which was then recrystallized from hexane to yield colorless prisms having a melting point of 66°-67° C.

Sources & evidence

ORD record
ord-e003ff049ccf4d93ae049e28aed2aa9b
Source dataset
uspto-grants-1997_03
Patent number
US05614544

Reaction notes

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