HCID 19965629, compound → HCID 54023049, compound

HRID 977267Notes

Reaction equation

HRID 977267 reaction equation
[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[N:4][C:3]=1[CH2:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18](/[CH:21]=[CH:22]/[CH2:23][OH:24])=[CH:17][CH:16]=1>[O-2].[O-2].[Mn+4]>[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[N:4][C:3]=1[CH2:13][CH2:14][C:15]1[CH:16]=[CH:17][C:18]([CH:21]=[CH:22][CH:23]=[O:24])=[CH:19][CH:20]=1

Participants

3

Reactant 1

HCID 19965629HCID 19965629, compound

Product 1

HCID 54023049HCID 54023049, compound

Reagents, catalysts & solvents 1

HCID 178418406HCID 178418406, compoundCatalyst

Procedure

(E)-3-[4-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl]phenyl]-2-propenol was oxidized with activated manganese dioxide in the same manner as in Reference Example 25 to yield 4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]cinnamaldehyde, which was then recrystallized from ethyl acetate-hexane to yield colorless prisms having a melting point of 99°-100° C.

Sources & evidence

ORD record
ord-46a4a346cc2d4896a76f8d7be7a24601
Source dataset
uspto-grants-1997_03
Patent number
US05614544

Reaction notes

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