Methanol → 1-Benzyl-4-hydroxy-3-isobutylpiperidine
Reaction equation
[BH4-:1].[CH2:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[N:10]1[CH2:11][CH:12]([CH2:17][CH:18]([CH3:19])[CH3:20])[C:13](=[O:16])[CH2:14][CH2:15]1.[CH3:21][OH:22].[Na+:2]>>[CH2:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[N:10]1[CH2:11][CH:12]([CH2:17][CH:18]([CH3:19])[CH3:20])[CH:13]([OH:16])[CH2:14][CH2:15]1Participants
5
Sources & evidence
- ORD record
- ord-2b259bdcc8a647fe8015aff28b257d07
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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