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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 977377Generated: October 31, 2026

Ethanol → HCID 57187766, compound

https://huagongshe.com/reaction/977377

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactant(2s)-Glycidyl indol-4-yl etherHCID 10943254—
ReactantHCID 11310393HCID 11310393—
SolventDimethyl SulfoxideHCID 679—
ProductHCID 57187766HCID 57187766—

Reaction Steps

The title compound was prepared in a fashion similar to that described in Example 1 using (S)-(+)-4-(oxiranylmethoxy)-1H-indole (0.389 g, 2.05 mmol) and 7-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (0.400 g, 1.87 mmol) using ethanol as reaction solvent. Yield 0.292 g (39%) as an orange foam. mp 155°-158° C. FDMS m/e=401 (M+ of free base). α[D]589 =+5.9 (c=1.05, dimethylsulfoxide).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05614523
Source datasetuspto-grants-1997_03
ORD IDord-c7c2b367f6804e159eb445323921e608
Source noteuspto-grants-1997_03