Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Piperonylamine → 6-trifluoromethyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Piperonylamine | HCID 2723901 | — |
| 반응물 | 6-(Trifluoromethyl)indole | HCID 2777523 | — |
| 생성물 | 6-trifluoromethyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 11242561 | — |
반응 단계
The title compound was prepared in a fashion similar to that described in Preparation 30 from 6-trifluoromethylindole (4.0 g, 22 mmol) and 4-piperidone hydrochloride hydrate (6.6 g, 43 mmol). The product was isolated as a white solid. Yield 3.7 g (64%). mp °C. FDMS m/e=266 (M+ of free base).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05614523 |
| 출처 데이터셋 | uspto-grants-1997_03 |
| ORD ID | ord-a3edc138d8bc47408c48b14d42d312fe |
| 출처 메모 | uspto-grants-1997_03 |