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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 977456Generated: October 31, 2026

Trifluoroacetic acid → 4'-[[2-n-Propyl-4-methyl-6-(imidazo[1,2-a]pyrimidin-2-yl)-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylic acid

https://huagongshe.com/reaction/977456

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 19965039HCID 19965039—
SolventDichloromethaneHCID 6344—
Product4'-[[2-n-Propyl-4-methyl-6-(imidazo[1,2-a]pyrimidin-2-yl)-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylic acidHCID 19964734—

Reaction Steps

Prepared analogously to Example 1 from tert.-butyl 4'-[[2-n-propyl-4-methyl-6-(imidazo[1,2-a]pyrimidin-2-yl)-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate and trifluoroacetic acid in methylene chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05614519
Source datasetuspto-grants-1997_03
ORD IDord-7853140be3364061afcf5d10e89f56f3
Source noteuspto-grants-1997_03