HRID977500

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCc1nc2c(C)cc(-c3nc(C)c(C)o3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1

HCID67708414

未命名化合物

HCID86750142

未命名化合物

PRODUCTS

生成物

结构：CCCc1nc2c(C)cc(-c3nc(C)c(C)n3C(C)C)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1

HCID53987628

未命名化合物

PROCEDURE

实验过程

Prepared analogously to. Example 146 from tert.butyl 4'-[[2-n-propyl-4-methyl-6-(4,5-dimethyl-oxazol-2-yl)-1H-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate and N-isopropyl-formamide/isopropylamine.

WORKUP

后处理

customPrepared analogously to

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e2c6b9bfc9f54639bd5252c1e2aa266c
来源数据集: uspto-grants-1997_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05614519
来源说明: uspto-grants-1997_03

反应 SMILES

[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[C:17]([C:22]([O:24]C(C)(C)C)=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:12][CH:11]=2)[C:7]2[CH:29]=[C:30]([C:34]3O[C:36](C)=[C:37](C)[N:38]=3)[CH:31]=[C:32]([CH3:33])[C:6]=2[N:5]=1)[CH2:2][CH3:3].[CH:41]([NH:44][CH:45]=O)([CH3:43])[CH3:42].[CH:47](N)(C)C>>[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:11]=[CH:12][C:13]([C:16]3[C:17]([C:22]([OH:24])=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:14][CH:15]=2)[C:7]2[CH:29]=[C:30]([C:34]3[N:44]([CH:41]([CH3:42])[CH3:43])[C:45]([CH3:47])=[C:37]([CH3:36])[N:38]=3)[CH:31]=[C:32]([CH3:33])[C:6]=2[N:5]=1)[CH2:2][CH3:3]