Hydrochloric Acid → HCID 19966035, compound

Participants

Reaction Steps

100 mg of N-{2-[3-(1-imidazolyl)propoxy]methyl-6-methylthiophenyl}-2-(9H-xanthen-9-yl)acetamide (prepared as described in Example 1) were dissolved in a mixture of methanol and methylene chloride. An excess of concentrated aqueous hydrochloric acid was added to the solution, and then the solvent was removed by distillation under reduced pressure. The resulting residue was dissolved in methanol, and diethyl ether was added to produce 85 mg of the title compound as crystals, melting at 175°-184° C.

Provenance & Evidence