HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Chloride → 5-(benzylthio)-4-chloro-2-phenylpyridazin-3(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Chloride | HCID 7503 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 4,5-Dichloro-2-phenyl-3(2H)-pyridazinone | HCID 72813 | — |
| Reactant | HCID 20204599 | HCID 20204599 | — |
| Reactant | Sodium hydrogen sulphide | HCID 86586439 | — |
| Product | 5-(benzylthio)-4-chloro-2-phenylpyridazin-3(2H)-one | HCID 735800 | — |
Reaction Steps
Compounds of the type IV are known, but the conventional methods of preparation entail two stages, starting from the dihalo compound II, or give undesirable by-products. Chem. Abstr. 68, (1968), 2906 c describes the preparation of 4-chloro-5-mercapto-2-phenylpyridazin-3(2H)-one (V) starting from 4,5-dichloro-2-phenylpyridazin-3(2H)-one (II, R1 =C6H5, X=Cl) and sodium hydrogen sulfide, the product (V) being reacted with benzyl chloride and sodium hydroxide and ammonium hydroxide to give the desired compound 5-benzylthio-4-chloro-2-phenyl-pyridazin-3-(2H)-one. ##STR5##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04663324 |
| Source dataset | uspto-grants-1987_05 |
| ORD ID | ord-103b01ae19844906b7c5376268d9426c |
| Source note | uspto-grants-1987_05 |