HCID 131715121, compound → HCID 131715122, compound

HRID 977972Notes

Reaction equation

HRID 977972 reaction equation
[CH2:1]([O:3][C:4](=[O:25])[CH2:5][C:6](=[O:24])[N:7]([CH2:14][C:15]1[CH:20]=[CH:19][C:18]([N+:21]([O-])=O)=[CH:17][CH:16]=1)[CH2:8][CH2:9][C:10]([O:12][CH3:13])=[O:11])[CH3:2]>[Pd].C(O)C>[CH2:1]([O:3][C:4](=[O:25])[CH2:5][C:6](=[O:24])[N:7]([CH2:14][C:15]1[CH:20]=[CH:19][C:18]([NH2:21])=[CH:17][CH:16]=1)[CH2:8][CH2:9][C:10]([O:12][CH3:13])=[O:11])[CH3:2]

Participants

4

Reactant 1

HCID 131715121HCID 131715121, compound

Product 1

HCID 131715122HCID 131715122, compoundYield 87.7%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Ethyl[N-(p-nitrobenzyl)-N-(methoxycarbonylethyl)carbamoyl]acetate (1.01 g) obtained in Example 32-(2), ethanol (10 ml) and 10% Pd/C (150 mg) are treated in the same manner as described in Example 33, whereby ethyl[N-(p-aminobenzyl)-N-(methoxycarbonylethyl)carbamoyl]acetate (810 mg, 87.5%) is obtained as pale yellow oil.

Sources & evidence

ORD record
ord-82bac9a1a32e4f3daa193f07a99c0e44
Source dataset
uspto-grants-1987_05
Patent number
US04663319

Reaction notes

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