HCID 12689967, compound → HCID 20204621, compound

HRID 977976Notes

Reaction equation

HRID 977976 reaction equation
[ClH:1].C(N1CCCC(O)(C2C=CC=CC=2)C1)(C)C.Cl.[C:19]([N:23]1[CH2:28][CH2:27][CH2:26][C:25](O)([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH2:24]1)([CH3:22])([CH3:21])[CH3:20]>>[ClH:1].[C:19]([N:23]1[CH2:28][CH2:27][CH:26]=[C:25]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH2:24]1)([CH3:22])([CH3:20])[CH3:21]

Participants

3

Reactant 2

HCID 12689967HCID 12689967, compoundHCID 20204619HCID 20204619, compound

Product 1

HCID 20204621HCID 20204621, compound

Procedure

By following the procedure indicated in step (d) of Preparation II and replacing the N-isopropyl-3-hydroxy-3-phenylpiperidine hydrochloride with the N-tert.-butyl-3-hydroxy-3-phenylpiperidine hydrochloride, the N-tert.-butyl-3-phenyl-1,2,5,6-tetrahydropyridine hydrochloride was obtained.

Sources & evidence

ORD record
ord-b50ffa80b83d4752910e066d67fd832c
Source dataset
uspto-grants-1987_05
Patent number
US04663328

Reaction notes

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