Sodium Hydroxide → HCID 57002693, compound

Participants

Reaction Steps

For 1 hour, 1 g of 4,7-dihydro-7-ethyl-2-hydroxyiminomethyl-4-oxo-thieno[2,3-b]pyridine-5-carboxylic acid ethyl ester was refluxed in 30 ml of 10%-sodium hydroxide. After cooling, the solution was filtered and acidified with 10%-hydrochloric acid. After filtration 4,7-dihydro-7-ethyl-2-hydroxyiminomethyl-4-oxo-thieno[2,3-b]pyridine-5-carboxylic acid was obtained in a yield of 80%. M.P.: 315°-317° C. (N,N-dimethylformamide).

Provenance & Evidence