3,4-Dimethoxy-1,2,5-thiadiazole 1,1-dioxide → N'-(4-methoxy-1,1-dioxo-1,2,5-thiadiazol-3-yl)-N,N-dimethylhex-2-yne-1,6-diamine

Participants

Reaction Steps

In a similar manner to Example 1, 3,4-dimethoxy-1,2,5-thiadiazole-1,1-dioxide (1.0 g) and 6-(dimethylamino)hex-4-ynylamine (0.79 g) were reacted to give a solution of 3-methoxy-4-[6-dimethylaminohex-4-ynylamino]-1,2,5-thiadiazole-1,1-dioxide. Reaction with ammonia and purification as in Example 1 gave the title compound (0.62 g), m.p. 183°-5° C. (recrystallisation from acetonitrile).

Provenance & Evidence