反应详情

3,4-Dichloroaniline, 13.7 g (0.084 mole), is dissolved in 200 ml dichloroethane, containing 25 ml pyridine. The solution is stirred at room temperature while nonanoyl chloride, 14.6 g (0.086 mole), is added slowly. The solution is stirred two hours. Excess pyridine is removed by washing the product with 4N hydrochloric acid. A crude product is crystallized from 95% ethanol. There is obtained N-(3,4-dichlorophenyl) nonanamide, a white crystalline solid, (M.P. 68.5-69.0%). Analysis shows 4.52% nitrogen and 23.26% chlorine as against calculated values of 4.63% and 23.48% respectively for C15H21Cl2NO.

1. additionis added slowly
2. customExcess pyridine is removed
3. washby washing the product with 4N hydrochloric acid
4. customA crude product is crystallized from 95% ethanol