Bromine → HCID 13849524, compound

HRID 978113Notes

Reaction equation

HRID 978113 reaction equation
[OH:1][C:2]1[CH:16]=[CH:15][C:5]2[C:6]([CH3:14])=[C:7]([C:9]([O:11][CH2:12][CH3:13])=[O:10])[O:8][C:4]=2[CH:3]=1.[Br:17]Br>C(Cl)Cl>[Br:17][C:3]1[C:4]2[O:8][C:7]([C:9]([O:11][CH2:12][CH3:13])=[O:10])=[C:6]([CH3:14])[C:5]=2[CH:15]=[CH:16][C:2]=1[OH:1]

Participants

4

Reactant 2

HCID 24408BromineHCID 15560986Ethyl 6-hydroxy-3-methyl-2-benzofurancarboxylate

Product 1

HCID 13849524HCID 13849524, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

A suspension of ethyl 6-hydroxy-3-methylbenzofuran-2-carboxylate (220 mg, 1 mmole) in methylene chloride (6 ml) was treated very slowly with a solution of bromine (160 mg, 1 mmole) in methylene chloride (4 ml) and with efficient stirring.

Sources & evidence

ORD record
ord-4c36afc1038a44c88d154e1ef369fc97
Source dataset
uspto-grants-1987_05
Patent number
US04663347

Reaction notes

Loading…