反应详情

A mixture of 3-(4-hydroxy-3-methylbenzofuran-2-yl)propionic acid (400 mg, 1.8 mmole) in 1% sulfuric acid in ethanol was kept at room temperature for 18 hours. The mixture was concentrated. The residue was taken up in diethyl ether, washed with water twice, dried with Na2SO4, filtered, concentrated and chromatographed to obtain 280 mg of the title compound, m.p. 61°-63° C.

1. concentrationThe mixture was concentrated
2. washwashed with water twice
3. dry with materialdried with Na2SO4
4. filtrationfiltered
5. concentrationconcentrated
6. customchromatographed