HCID 20205086, compound → HCID 20205093, compound

HRID 978125Notes

Reaction equation

HRID 978125 reaction equation
[OH:1][C:2]1[C:7]2[C:8]([CH3:16])=[C:9]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[O:10][C:6]=2[C:5](C(=O)C)=[CH:4][CH:3]=1.C(C1C=CC2O[C:29]([C:31]([O:33]CC)=[O:32])=C(C)C=2C=1O)(=O)C>>[CH2:14]([O:13][C:11]([C:9]1[O:10][C:6]2[C:5]([O:33][C:31](=[O:32])[CH3:29])=[CH:4][CH:3]=[C:2]([OH:1])[C:7]=2[C:8]=1[CH3:16])=[O:12])[CH3:15]

Participants

3

Reactant 2

HCID 20205086HCID 20205086, compoundHCID 20205101Ethyl 5-acetyl-4-hydroxy-3-methylbenzofuran-2-carboxylate

Product 1

HCID 20205093HCID 20205093, compound

Procedure

Following the procedure of Example 156 but substituting Ethyl 4-hydroxy-7-acetyl-3-methylbenzofuran-2-carboxylate for the compound of Example 155. There is obtained the intermediate Ethyl-7-acetoxy-4-hydroxy-3-methylbenzofuran-2-carboxylate which is hydrolyzed in an aqueous acetic acid solution of hydrochloric acid (6 hours, 100° C.) to give the title compound.

Sources & evidence

ORD record
ord-47bb365ba4ba4cf1b6a6f8588b6b253d
Source dataset
uspto-grants-1987_05
Patent number
US04663347

Reaction notes

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