Ammonia → 2,2,6,6-Tetramethyl-4-piperidone

HRID 978186Notes

Reaction equation

HRID 978186 reaction equation
[CH3:1][C:2](=[CH:4][C:5](=[O:10])[CH:6]=[C:7]([CH3:9])[CH3:8])[CH3:3].[NH3:11]>CC(C)=O>[CH3:1][C:2]1([CH3:3])[NH:11][C:7]([CH3:9])([CH3:8])[CH2:6][C:5](=[O:10])[CH2:4]1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 10438Phorone2×

Product 1

HCID 132202,2,6,6-Tetramethyl-4-piperidoneYield 70%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Heinz Annalen der Chemie 203 336 (1880) converts acetone to phorone in about 30% yield, and reacts phorone with ammonia to form triacetone amine in 70% yield.

Sources & evidence

ORD record
ord-10c314371ac143fa8e24c70273576b49
Source dataset
uspto-grants-1987_05
Patent number
US04663459

Reaction notes

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