4-Hydroxybenzyl Alcohol → 1-(4-Hydroxybenzyl)imidazole

HRID 978233Notes

Reaction equation

HRID 978233 reaction equation
[OH:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6]O)=[CH:4][CH:3]=1.[NH:10]1[CH:14]=[CH:13][N:12]=[CH:11]1>>[N:10]1([CH2:6][C:5]2[CH:8]=[CH:9][C:2]([OH:1])=[CH:3][CH:4]=2)[CH:14]=[CH:13][N:12]=[CH:11]1

Participants

3

Reactant 2

HCID 1254-Hydroxybenzyl AlcoholHCID 795Imidazole

Product 1

HCID 1938221-(4-Hydroxybenzyl)imidazole

Procedure

In a manner analogous to that described in the second paragraph of Example 13, from 4-hydroxybenzyl alcohol and imidazole, 4-[(1-imidazolyl)methyl]phenol was obtained.

Sources & evidence

ORD record
ord-7e5253d5fc07453ab9aa29bf08dd7dc9
Source dataset
uspto-grants-1987_05
Patent number
US04663462

Reaction notes

Loading…