2,5-Dimethyl-3-piperazin-1-ylpyrazine → (RS)-4-(3',6'-Dimethyl-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-carbonyl)-3-phenyl-1-(2-trifluoromethyl-benzenesulfonyl)-imidazolidin-2-one

HRID 97825Notes

Reaction equation

HRID 97825 reaction equation
[CH3:29][c:30]1[c:31]([N:37]2[CH2:38][CH2:39][NH:40][CH2:41][CH2:42]2)[n:32][c:33]([CH3:36])[cH:34][n:35]1.[O:1]=[C:2]1[N:3]([S:16](=[O:17])(=[O:18])[c:19]2[c:20]([C:25]([F:26])([F:27])[F:28])[cH:21][cH:22][cH:23][cH:24]2)[CH2:4][CH:5]([C:13](=[O:14])[OH:15])[N:6]1[c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1>>[O:1]=[C:2]1[N:3]([S:16](=[O:17])(=[O:18])[c:19]2[c:20]([C:25]([F:26])([F:27])[F:28])[cH:21][cH:22][cH:23][cH:24]2)[CH2:4][CH:5]([C:13](=[O:15])[N:40]2[CH2:39][CH2:38][N:37]([c:31]3[c:30]([CH3:29])[n:35][cH:34][c:33]([CH3:36])[n:32]3)[CH2:42][CH2:41]2)[N:6]1[c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1

Participants

3

Reactant 2

HCID 38119102,5-Dimethyl-3-piperazin-1-ylpyrazineHCID 67141210(RS)-2-oxo-3-phenyl-1-(2-trifluoromethyl-benzenesulfonyl)-imidazolidine-4-carboxylic acid

Product 1

HCID 25027494(RS)-4-(3',6'-Dimethyl-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-carbonyl)-3-phenyl-1-(2-trifluoromethyl-benzenesulfonyl)-imidazolidin-2-one

Sources & evidence

ORD record
ord-ecf7ba06d08449fc9044bc596983f62e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…