HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichloroaniline → 5-Chloro-3-(3,4-dichlorophenyl)-4-thiazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichloroaniline | HCID 7257 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-(3,4-Dichlorophenyl)-1,3-thiazolidin-4-one | HCID 4585437 | — |
| Reactant | Thiazolidinone | HCID 20553328 | — |
| Product | 5-Chloro-3-(3,4-dichlorophenyl)-4-thiazolidinone | HCID 13853453 | — |
Reaction Steps
3,4-Dichloroaniline was converted to 3-(3,4-dichlorophenyl)-4-thiazolidinone as outlined in Example 1. This thiazolidinone, which had a melting point of 145°-146° C., was chlorinated with thionyl chloride to form 5-chloro-3-(3,4-dichlorophenyl)-4-thiazolidinone having a melting point of 100°-103° C. Recrystallization of this product from ethanol gave 3-(3,4-dichlorophenyl)-5-ethoxy-4-thiazolidinone which had a melting point of 61°-65° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04664694 |
| Source dataset | uspto-grants-1987_05 |
| ORD ID | ord-beee820f7b0c4a32aec5ec4e80c04404 |
| Source note | uspto-grants-1987_05 |