2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 54519904, compound

Participants

Reaction Steps

2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (5.0 g) was added to a solution of 1-(4,5,6-trimethyl-2,3-dihydrobenzo[b]furan-7-yl)-but-1-en-3-one (5.0 g) in toluene (100 ml) and the mixture was stirred at room temperature for a period of 24 hours. The solvent was evaporated by distillation under reduced pressure and the residue was purified by column chromatography over silica gel with dichloromethane elution to give 1-(4,5,6-trimethylbenzo[b]furan-7-yl)but-1-en-3-one (4.2 g; 85%) as a pale yellow solid, mp 99° C.

Provenance & Evidence