Phenylhydrazine → N-(2-Methoxyethyl)-2-phenylhydrazinecarbothioamide

Participants

Reaction Steps

In benzene was dissolved 11.7 g of 2-methoxyethyl isothiocyanate with stirring, and 11.9 g of phenylhydrazine was added thereto at room temperature. The resulting mixture was heat refluxed for 6 hours, followed by cooling. The thus precipitated crystals were removed by filtration to obtain 4-(2-methoxyethyl)-1-phenylthiosemicarbazide (yield: 66.7%). This product can be used in the subsequent reaction without further purification.

Provenance & Evidence