Sulfuric Acid → HCID 20139108, compound

HRID 978363Notes

Reaction equation

HRID 978363 reaction equation
[C:1]([OH:4])(=[O:3])[CH3:2].N[C:6]1[CH:19]=[CH:18][C:9]2[C:10](=O)O[C:12]([O:14][CH2:15][CH3:16])=[N:13][C:8]=2[CH:7]=1.[S:20](=[O:24])(=[O:23])([OH:22])[OH:21]>O>[S:20]([OH:24])([OH:23])(=[O:22])=[O:21].[CH2:15]([O:14][C:12]1[O:3][C:1](=[O:4])[C:2]2[C:18]([CH2:9][CH3:10])=[CH:19][CH:6]=[CH:7][C:8]=2[N:13]=1)[CH3:16]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 20139312HCID 20139312, compound

Product 1

HCID 20139108HCID 20139108, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

7-amino-2-ethoxy-4H-3,1-benzoxazin-4-one acetate (1.0 g) is dissolved in 50 ml water containing a stoichiometric equivalent of sulfuric acid, and the solution evaporated to dryness. The product is suspended in ether and filtered, air dried and recrystallized from methanol/acetone to yield 2-ethoxy-5-ethyl-4H-3,1-benzoxazin-4-one sulfate.

Workup

  1. customthe solution evaporated to dryness
  2. filtrationfiltered
  3. customair dried
  4. customrecrystallized from methanol/acetone

Sources & evidence

ORD record
ord-c2d05f829120469696234e61aea8c543
Source dataset
uspto-grants-1987_05
Patent number
US04665070

Reaction notes

Loading…