Ethyl chloroformate → HCID 20202887, compound

Participants

Reaction Steps

To a stirred mixture of 7 parts of ethyl 2-amino-4-(phenylmethoxy)benzoate and 45 parts of dimethylbenzene were added dropwise 3.25 parts of ethyl carbonochloridate. Upon completion, stirring was continued for 6 hours at reflux temperature. The reaction mixture was cooled and the solvent was evaporated. The residue was crystallized from 2,2'-oxybispropane. The product was filtered off and dried, yielding 6.1 parts (71%) of ethyl 2-[(ethoxycarbonyl)-amino]-4-(phenylmethoxy)benzoate (15).

Provenance & Evidence