反应详情

To a stirred mixture of 100 g (0.62 moles) p-methylcinnamic acid in methylene chloride (about 30 ml), 88 g (0.74 moles) thionyl chloride was added dropwise. The reaction mixture was then refluxed for 24 hours. The methylene chloride was removed under reduced pressure and heat to give the corresponding p-methylcinnamic acid chloride. Fresh methylene chloride was added to the acid chloride; half of which was used in Step (b).

1. additionwas added dropwise
2. temperatureThe reaction mixture was then refluxed for 24 hours
3. customThe methylene chloride was removed under reduced pressure
4. temperatureheat