Potassium Carbonate → HCID 20203315, compound

Participants

Reaction Steps

A mixture of 29.4 g (0.350 moles) methoxyaminehydrochloride and 50 g (0.36 moles) potassium carbonate in about 200 ml ice water was stirred, maintaining the temperature below -5° C. until the reactants were dissolved. To that solution, 50 g (0.302 moles) 4-cyano-benzoylchloride were dropped in slowly, maintaining the temperature of the reaction mixture below 0° C. during the addition. The reaction mixture was stirred overnight. The reaction mixture was suction-filtered. The residue, containing the crude product was dried in a heated vacuum oven and then washed with hexane (about 100 ml) and ether (about 2-3 ml) to give the product an off-white solid.

Provenance & Evidence