化工社化工社 化学情報印刷レポート · 研究参考用
Hydrazine hydrate (1:1) → 4-(1-Adamantyl)-3-thiosemicarbazide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 反応物 | Adamantyl isothiocyanate | HCID 107279 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 4-(1-Adamantyl)-3-thiosemicarbazide | HCID 762709 | 96.1% |
反応手順
A solution of 1.5 g (0.03 mol) of hydrazine hydrate in 50 ml of EtOH was treated with 3.86 g (0.02 mol) of 1-adamantyl isothiocyanate, and stirred for one hour at room temperature. The product was collected and washed two times with EtOH, affording 4.33 g (96%) of 4-(1-adamantyl)-3-thiosemicarbazide, mp 206°-207° C. This thiosemicarbazide is disclosed in Chemical Abstracts, 70:11223 (1969); and in U.S. Pat. No. 3,406,180.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04665173 |
| 出典データセット | uspto-grants-1987_05 |
| ORD ID | ord-0d8b3fef222e46efa5dd64bfae9d5d48 |
| 出典メモ | uspto-grants-1987_05 |