HCID 53748875, compound → HCID 13827307, compound

Participants

Reaction Steps

A slurry of 11.2 gm 6-(2-phenylethenyl)-1(2H)-phthalazinone, from the previous example, in 115 ml dimethylformamide was hydrogenated with 1.0 gm 10% palladium on carbon catalyst at 50 psig for 3 hours. The catalyst was filtered off and rinsed with a little dimethylformamide. The filtrate was added to 5 volumes of water, stirred for a few minutes, filtered, washed with water and air dried. Wt=7.8 gm, m.p.=190°-193°. After recrystallization from 80 ml n-butanol the product weighed 6.4 gm and melted at 192°-193°.

Provenance & Evidence