Hydrochloric Acid → HCID 13827308, compound

Participants

Reaction Steps

6-[2-(4-Dimethylaminophenyl)ethenyl]-1(2H)-phthalazinone (2.6 gm of a mixture of cis/trans isomers) in methanol (100 ml)/5N.HCl (10 ml) was hydrogenated at 60 psig over 5% Pd/C (0.5 gm) for 20 hours. The reaction mixture was heated to dissolve the product and then filtered from the catalyst. The cooled filtrate was filtered to give the saturated product as a solid (2.3 gm), mp 257°-9° C.

Provenance & Evidence