N,N-Dimethylaminoethyl chloride hydrochloride → HCID 13827291, compound

HRID 978661Notes

Reaction equation

HRID 978661 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]2[CH:11]=[C:12]3[C:17](=[CH:18][CH:19]=2)[C:16](=[O:20])[NH:15][N:14]=[CH:13]3)=[CH:4][CH:3]=1.Cl.[CH3:22][N:23]([CH3:27])[CH2:24][CH2:25][Cl:26]>>[ClH:26].[OH:1][C:2]1[CH:3]=[CH:4][C:5](/[CH:8]=[CH:9]/[C:10]2[CH:11]=[C:12]3[C:17](=[CH:18][CH:19]=2)[C:16](=[O:20])[N:15]([CH2:25][CH2:24][N:23]([CH3:27])[CH3:22])[N:14]=[CH:13]3)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 11636816N,N-Dimethylaminoethyl chloride hydrochlorideHCID 13827271HCID 13827271, compound

Product 1

HCID 13827291HCID 13827291, compound

Procedure

Following the procedure of Example 15 above trans-6-[2-(4-hydroxyphenyl)ethenyl]-1(2H)phthalazinone (19.8 ) and 2-dimethylaminoethyl chloride hydrochloride (17.3 g) were reacted to give the 2-(2-dimethylaminoethyl)derivative as the hydrochloride (16 g), mp 283°-285° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-5df8e936da434562a0b3a92cdb9e1155
Source dataset
uspto-grants-1987_05
Patent number
US04665181

Reaction notes

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