HCID 21293345, compound → HCID 13827309, compound

Participants

Reaction Steps

Trans-6-[2-(4-Hydroxyphenyl)ethenyl]-2-(3-dimethylaminopropyl)-1(2H)-phthalazinone hydrochloride (5 g) in methanol (100 ml) and water (10 ml) was hydrogenated at 50 psi over 10% Pd/C (0.5 g). After 6 hours the catalyst was filtered and the filtrate was diluted with ether (600 ml). The precipitated product was filtered to give 4.3 g of the saturated product as the hydrochloride mp. 234°-236° C.

Provenance & Evidence