Triphenylphosphine → (8-Tetrahydropyranyloxyoctyl)triphenylphosphonium bromide

Participants

Reaction Steps

A solution of 1-bromo-8-tetrahydropyranyloxyoctane (9.8 g) and triphenyl phosphine (8.8 g) in acetonitrile (50 ml) was heated under reflux for 8 hours. The solution was evaporated and the residue washed with ether to give the title compound as a hygroscopic white solid which was dried by addition of benzene and re-evaporation.

Provenance & Evidence