HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 13647623, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Chlorosulfonyl isocyanate | HCID 70918 | — |
| Reactant | 6-Fluoro-1,3-dihydro-5-methyl-2H-indol-2-one | HCID 13565669 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 13647623 | HCID 13647623 | — |
Reaction Steps
Following the procedure of Example 2, the title compound was prepared from 6-fluoro-5-methyl-2-oxindole (1.0 g, 6.0 mmole), chlorosulfonyl isocyanate (1.03 g, 7.3 mmole), toluene (30 ml). Water (5 ml) was used for the hydrolysis step. Yield=0.58 g, 46%. M.P. 200°-203° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04665194 |
| Source dataset | uspto-grants-1987_05 |
| ORD ID | ord-8a0d2b403eb644cea10a12206f271ee9 |
| Source note | uspto-grants-1987_05 |