HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 5,6-dimethoxybenzo[b]thiophene-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 5,6-dimethoxy-1-benzothiophene-2-carboxylic acid | HCID 268620 | — |
| Product | Ethyl 5,6-dimethoxybenzo[b]thiophene-2-carboxylate | HCID 45104330 | — |
Reaction Steps
5,6-Dimethoxy-benzo[b]thiophene-2-carboxylic acid (10 g) was suspended in ethanol (80 ml) and the mixture was stirred and heated at reflux for 5 hours. The resultant solution was evaporated to dryness and then crystallised from dichlolormethane:methanol to give 5,6-dimethoxy-benzo[b]thiophene-2-carboxylic acid ethyl ester as a white solid (9.5 g), m.p. 84°-85° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04665206 |
| Source dataset | uspto-grants-1987_05 |
| ORD ID | ord-d6d3dca88cd240e788284457aaa2b30b |
| Source note | uspto-grants-1987_05 |