HCID 21289506, compound → HCID 21289505, compound

HRID 978774Notes

Reaction equation

HRID 978774 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][C:8]2[CH2:17][CH2:16][C:15]3[CH:14]=[C:13]([C:18]([O:20][CH2:21][CH3:22])=[O:19])[CH:12]=[CH:11][C:10]=3[CH:9]=2)[CH:2]=1>C(O)C.[C].[Pd]>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][CH:8]2[CH2:17][CH2:16][C:15]3[CH:14]=[C:13]([C:18]([O:20][CH2:21][CH3:22])=[O:19])[CH:12]=[CH:11][C:10]=3[CH2:9]2)[CH:2]=1

Participants

4

Reactant 1

HCID 21289506HCID 21289506, compound

Product 1

HCID 21289505HCID 21289505, compoundYield 99.3%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

1.8 g of ethyl 6-(3-pyridylmethyl)-7,8-dihydro-2-naphthalenecarboxylate was dissolved in 100 ml of ethanol and 1 g of 10% palladium carbon was added thereto. The mixture was catalytically reduced. After absorption of hydrogen gas was completed, the catalyst was removed by filtration. The filtrate was concentrated in vacuo to give 1.8 g of ethyl 6-(3-pyridylmethyl)-5,6,7,8-tetrahydro-2-naphthalenecarboxylate as an oil.

Workup

  1. customAfter absorption of hydrogen gas
  2. customthe catalyst was removed by filtration
  3. concentrationThe filtrate was concentrated in vacuo

Sources & evidence

ORD record
ord-48be90f9ec2a43d4803f6f07bd4a1d0e
Source dataset
uspto-grants-1987_05
Patent number
US04665188

Reaction notes

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