4'-Hydroxyacetophenone → p-Acetylphenyl acetate

HRID 978798Notes

Reaction equation

[CH3:1][C:2]([C:4]1[CH:5]=[CH:6][C:7]([OH:10])=[CH:8][CH:9]=1)=[O:3].[C:11](OC(=O)C)(=[O:13])[CH3:12]>>[CH3:1][C:2]([C:4]1[CH:9]=[CH:8][C:7]([O:10][C:11]([CH3:12])=[O:13])=[CH:6][CH:5]=1)=[O:3]

Participants

Reactant 2

HCID 74694'-Hydroxyacetophenone

HCID 7918Acetic Anhydride

Product 1

HCID 83063p-Acetylphenyl acetate

Procedure

The following example illustrates the reaction of 4-hydroxyacetophenone (4-HAP) with acetic anhydride to form 4-acetoxyacetophenone (4-AAP).

Sources & evidence

ORD record: ord-664c01b4551941eab85e8b6f6e197794
Source dataset: uspto-grants-1987_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04665215

Reaction notes

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