HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid monohydrate → (3S,4S)-3-amino-4-azido-2-oxoazetidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Reactant | (3S,4S)-4-azido-3-tritylamino-2-azetidinone | HCID 53771026 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | (3S,4S)-3-amino-4-azido-2-oxoazetidine | HCID 54269820 | — |
Reaction Steps
To a solution of 1.3 g of (3S,4S)-4-azido-3-tritylamino-2-oxoazetidine in 15 ml of acetone is added 0.736 g of p-toluenesulfonic acid monohydrate. The mixture is treated in a same manner to Reference Example 45B to give 0.886 g of tosyl salt of (3S,4S)-3-amino-4-azido-2-oxoazetidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04665067 |
| Source dataset | uspto-grants-1987_05 |
| ORD ID | ord-a83351d8636d426aac89df724d54814a |
| Source note | uspto-grants-1987_05 |