HRID979002

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN

HCID2973

Deferoxamine

C25H48N6O8

HCID7847

Acrolein

C3H4O

PRODUCTS

生成物

结构：C=CC=O.CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN

HCID131715138

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID679

Dimethyl sulfoxide

C2H6OS

2 次

PROCEDURE

实验过程

To a solution of polyacrolein (125 mg) in dimethylsulfoxide (2.5 ml), a solution of deferoxamine (105 mg) in dimethylsulfoxide (2.5 ml) was added, and the resultant mixture was agitated at room temperature for 3 hours to produce a solution containing the polyacrolein-deferixamine condensation product, which is useful as a non-radioactive carrier.

WORKUP

后处理

customto produce a solution
additioncontaining

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-512ffb435e5b4d9ab56cd3ade5c5004c
来源数据集: uspto-grants-1987_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04666697
来源说明: uspto-grants-1987_05

反应 SMILES

[CH2:1]=[CH:2][CH:3]=[O:4].[CH3:5][C:6]([N:8]([OH:43])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][NH:14][C:15]([CH2:17][CH2:18][C:19]([N:21]([OH:42])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][NH:27][C:28]([CH2:30][CH2:31][C:32]([N:34]([OH:41])[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][NH2:40])=[O:33])=[O:29])=[O:20])=[O:16])=[O:7]>CS(C)=O>[CH2:1]=[CH:2][CH:3]=[O:4].[CH3:5][C:6]([N:8]([OH:43])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][NH:14][C:15]([CH2:17][CH2:18][C:19]([N:21]([OH:42])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][NH:27][C:28]([CH2:30][CH2:31][C:32]([N:34]([OH:41])[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][NH2:40])=[O:33])=[O:29])=[O:20])=[O:16])=[O:7]