(4-Chlorophenoxy)acetic acid → HCID 13576356, compound

Participants

Reaction Steps

4.7 g (0.025 mol) of 4-chlorophenoxyacetic acid and 4.3 g (0.027 mol) of carbonyldiimidazole are heated under reflux in 100 of tetrahydrofuran for 15 minutes. After the mixture has been cooled, 6.7 g (0.025 mol) of 6-(3,4-dimethoxyphenyl)-5-hydroxymethyl-2,3,4,5-tetrahydropyridazin-3-one are added with stirring. After a reaction time of 5 hours, the mixture is concentrated at room temperature and the residue is worked up as in Example 5.

Provenance & Evidence