HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-dimethyl-4-nitro-1H-pyrazole-5-carbonitrile → 4-Amino-1,3-dimethyl-1H-pyrazole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-dimethyl-4-nitro-1H-pyrazole-5-carbonitrile | HCID 96507 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-Amino-1,3-dimethyl-1H-pyrazole-5-carbonitrile | HCID 12335816 | — |
Reaction Steps
Two-hundred and seventy-two g of 1,3-dimethyl-4-nitro-5-cyano-pyrazole was subjected to catalytic hydrogenation in methanol using a Raney nickel catalyst. The catalyst was filtered away and the filtrate concentrated. The product solidified, mp 109°-111° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04666908 |
| Source dataset | uspto-grants-1987_05 |
| ORD ID | ord-80572243f85a460c9c65208bd90fc4a8 |
| Source note | uspto-grants-1987_05 |