Sodium dithionate → HCID 13491969, compound

HRID 979070Notes

Reaction equation

HRID 979070 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N+:21]([O-])=O)[C:5]([OH:20])=[C:6]([CH2:8][C:9]2[CH:14]=[C:13]([Cl:15])[CH:12]=[C:11]([N+:16]([O-])=O)[C:10]=2[OH:19])[CH:7]=1.S(S([O-])(=O)=O)([O-])(=O)=O.[Na+].[Na+]>CO.O>[NH2:16][C:11]1[C:10]([OH:19])=[C:9]([CH2:8][C:6]2[CH:7]=[C:2]([Cl:1])[CH:3]=[C:4]([NH2:21])[C:5]=2[OH:20])[CH:14]=[C:13]([Cl:15])[CH:12]=1

Participants

4

Reactant 2

HCID 146045Sodium dithionateHCID 3757744HCID 3757744, compound

Product 1

HCID 13491969HCID 13491969, compoundYield 56.5%

Reagents, catalysts & solvents 1

HCID 22242641Methanol--water (1/1)Solvent

Procedure

To a suspension of 36.3 g (0.1 mole) of 1,1-bis(5-chloro-2-hydroxy-3-nitrophenyl)methane of Example 19 in 300 ml of methanol-water (1:1) was added 145 g (0.4 mole) of sodium dithionate. The mixture was stirred for 4 hours and then filtered. The solid was dissolved in 22 g of ethyl acetate and washed with water, dried over magnesium sulfate and concentrated to yield 16.9 g of product of m.p. 212°-215° C.

Workup

  1. filtrationfiltered
  2. dissolutionThe solid was dissolved in 22 g of ethyl acetate
  3. washwashed with water
  4. dry with materialdried over magnesium sulfate
  5. concentrationconcentrated

Sources & evidence

ORD record
ord-3d2a07bbbebf402eb582fb15db7e333f
Source dataset
uspto-grants-1987_05
Patent number
US04666909

Reaction notes

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