反应详情

To a solution of 0.469 g of 3,6-bis[2-(diethylamino)ethoxy]-4,5-acridinedimethanol in a mixture of 5.0 ml of anhydrous dimethyl sulfoxide and 2.8 ml of triethylamine is added a solution of 0.96 g of sulfur trioxide-pyridine complex in 5 ml of anhydrous dimethyl sulfoxide. The reaction mixture is stirred at room temperature for one hour. Most of the dimethyl sulfoxide is removed under reduced pressure without heat. The residue is treated first with 50 ml of saturated sodium bicarbonate solution and then with 50 ml of water, giving 0.35 g of the desired product as a yellow solid.

1. customMost of the dimethyl sulfoxide is removed under reduced pressure
2. temperaturewithout heat
3. additionThe residue is treated first with 50 ml of saturated sodium bicarbonate solution