Methyl Isocyanate → HCID 13562979, compound

HRID 979185Notes

Reaction equation

HRID 979185 reaction equation
[CH3:1][N:2]=[C:3]=[O:4].[NH:5]([CH:7]1[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[S:9](=[O:17])(=[O:16])[NH:8]1)[NH2:6]>O1CCOCC1>[CH3:1][NH:2][C:3]([NH:6][NH:5][C:7]1[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[S:9](=[O:17])(=[O:16])[N:8]=1)=[O:4]

Participants

4

Reactant 2

HCID 12228Methyl IsocyanateHCID 20201759HCID 20201759, compound

Product 1

HCID 13562979HCID 13562979, compoundYield 92.8%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

A solution of 3.7 g (0.55 mol) of methyl isocyanate in 30 ml of dioxane is added dropwise to 9.8 g (0.05 mol) of 3-hydrazino-2H,3H-1,2-benzisothiazole 1,1-dioxide in 100 ml of dioxane at room temperature. Stirring is continued for 1 hour, after which the product is filtered off under suction. 11.8 g (89% of theory) of 3-methylaminocarbonylhydrazino-1,2-benzisothiazole 1,1-dioxide of melting point 183° C. are obtained. The product can be recrystallized from ethanol.

Workup

  1. filtrationafter which the product is filtered off under suction

Sources & evidence

ORD record
ord-154aae76bc2a46c99ef7001cbf5d2264
Source dataset
uspto-grants-1987_05
Patent number
US04666930

Reaction notes

Loading…