Formic Acid → HCID 178521891, compound

HRID 979191Notes

Reaction equation

HRID 979191 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[CH:10][NH:11][CH:12]=2)=[CH:4][CH:3]=1.[CH:13](O)=[O:14]>>[NH:11]1[CH:12]=[C:8]([C:5]2[CH:4]=[CH:3][C:2]([NH:1][CH:13]=[O:14])=[CH:7][CH:6]=2)[N:9]=[CH:10]1

Participants

3

Reactant 2

HCID 284Formic AcidHCID 178507418HCID 178507418, compound

Product 1

HCID 178521891HCID 178521891, compound

Procedure

A solution of 4-(4-aminophenyl)-1-H-imidazole (10 g) in formic acid (100 ml) was refluxed for 4 hours and evaporated to dryness. The residue was dissolved in water, and the solution was filtered through charcoal and made basic to give 10 g of N-[4-(imidazol-4-yl)-phenyl]-formamide, M.p. 108°-109° C.

Workup

  1. customevaporated to dryness
  2. dissolutionThe residue was dissolved in water
  3. filtrationthe solution was filtered through charcoal

Sources & evidence

ORD record
ord-9b6ee49136de4cd8b8c27c178e817efa
Source dataset
uspto-grants-1987_05
Patent number
US04666932

Reaction notes

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